Код долголетия. 12 понятных и доступных способов сохранить здоровье, ясность ума и привлекательность на долгие годы — страница 40 из 47

Molecular Nutrition & Food Research 53, no. 9 (2009): 1156–1165.

34. Pazoki-Toroudi, H., et al. “Targeting mTOR Signaling by Polyphenols: A New Therapeutic Target for Ageing.” Ageing Research Reviews 31 (2016): 55–66.

35. Chiu, C. T., et al. “Hibiscus Sabdariffa Leaf Polyphenolic Extract Induces Human Melanoma Cell Death, Apoptosis, and Autophagy.” Journal of Food Science 80, no. 3 (2015): H649–658; Zhang, L., et al. “Polyphenol-Rich Extract of Pimenta Dioica Berries (Allspice) Kills Breast Cancer Cells by Autophagy and Delays Growth of Triple Negative Breast Cancer in Athymic Mice.” Oncotarget 6, no. 18 (2015): 16379–16395; Syed, D. N., et al. “Pomegranate Extracts and Cancer Prevention: Molecular and Cellular Activities.” Anti-Cancer Agents in Medicinal Chemistry 13, no. 8 (2013): 1149–1161.

36. Pazoki-Toroudi, H., et al. “Targeting mTOR Signaling by Polyphenols: A New Therapeutic Target for Ageing.” Ageing Research Reviews 31 (2016): 55–66; Morselli, E., et al. “Caloric Restriction and Resveratrol Promote Longevity Through the Sirtuin-1-Dependent Induction of Autophagy.” Cell Death Discovery 1 (2010): e10; Park, S. J., et al. “Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases.” Cell 148, no. 3 (2012): 421–433.

37. Zhou, G., et al. “Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action.” Journal of Clinical Investigation 108, no. 8 (2001): 1167–1174.

38. Zi, F., et al. “Metformin and Cancer: An Existing Drug for Cancer Prevention and Therapy.” Oncology Letters 15, no. 1 (2018): 683–690.

39. Bannister, C. A., et al. “Can People with Type 2 Diabetes Live Longer Than Those Without? A Comparison of Mortality in People Initiated with Metformin or Sulphonylurea Monotherapy and Matched, Non-Diabetic Controls.” Diabetes, Obesity and Metabolism 16, no. 11 (2014): 1165–1173.

40. Rudman, D., et al. “Effects of Human Growth Hormone in Men over 60 Years Old.” New England Journal of Medicine 323, no. 1 (1990): 1–6.

41. Inagaki, T., et al. “Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21.” Cell Metabolism 8, no. 1 (2008): 77–83.

42. Silberberg, M., and R. Silberberg. “Factors Modifying the Lifespan of Mice.” American Journal of Physiology 177, no. 1 (1954): 23–26.

43. Grandison, R. C., M. D. Piper, and L. Partridge. “Amino-Acid Imbalance Explains Extension of Lifespan by Dietary Restriction in Drosophila.” Nature 462, no. 7276 (2009): 1061–1064.

44. Kim, E., and K. L. Guan. “RAG GTPases in Nutrient-Mediated TOR Signaling Pathway.” Cell Cycle 8, no. 7 (2009): 1014–1018.

45. McCay, C. M., et al. “The Effect of Retarded Growth upon the Length of Life Span and upon the Ultimate Body Size.” The Journal of Nutrition 10, no. 1 (1935): 63–79.

46. Liu, K. A., et al. “Leucine Supplementation Differentially Enhances Pancreatic Cancer Growth in Lean and Overweight Mice.” Cancer Metabolism 2, no. 1 (2014): 6.

47. Huffman, S., and R. J. Jones. “Chronic Effect of Dietary Protein on Hypercholesteremia in the Rat.” Proceedings of the Society for Experimental Biology and Medicine 93, no. 3 (1956): 519–522.

48. Minor, R. K., et al. “Dietary Interventions to Extend Life Span and Health Span Based on Calorie Restriction.” Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 65, no. 7 (2010): 695–703.

49. Minor, R. K., et al. “Dietary Interventions to Extend Life Span and Health Span Based on Calorie Restriction.” Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 65, no. 7 (2010): 695–703; Levine, M. E., et al. “Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population.” Cell Metabolism 19, no. 3 (2014): 407–417; Solon-Biet, S. M., et al. “The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice.” Cell Metabolism 19, no. 3 (2014): 418–430.

50. Blagosklonny, M. V. “Rapamycin and Quasi-Programmed Aging: Four Years Later.” Cell Cycle 9, no. 10 (2010): 1859–1862.

Глава 4

1. Levine, M. E., et al. “Low Protein Intake Is Associated with a Major Reduction in IGF-1 Cancer, and Overall Mortality in the 65 and Younger but Not Older Population.” Cell Metabolism 19, no. 3 (2014): 407–417.

2. Fontana, L., et al. “Long-Term Effects of Calorie or Protein Restriction on Serum IGF-1 and IGFBP-3 Concentration in Humans.” Aging Cell 7, no. 5 (2008): 681–687.

3. De Bandt, J. P., and L. Cynober. “Therapeutic Use of Branched-Chain Amino Acids in Burn, Trauma, and Sepsis.” Journal of Nutrition 136, 1 Suppl (2006): 308s–313s.

4. Miller, R. A., et al. “Methionine-Deficient Diet Extends Mouse Lifespan, Slows Immune and Lens Aging, Alters Glucose, T4, IGF-I and Insulin Levels, and Increases Hepatocyte MIF Levels and Stress Resistance.” Aging Cell 4, no. 3 (2005): 119–325.

5. McCarty, M. F., and J. J. DiNicolantonio. “The Cardiometabolic Benefits of Glycine: Is Glycine an ‘Antidote’ to Dietary Fructose?” Open Heart (2014). 1:e000103. doi:10.1136/openhrt– 2014000103.

6. “Body Fat Calculator.” Activewebsite. Открыто по адресу www.active.com/fitness/calculators/bodyfat.

7. Rosedale, R. “The Good, the Bad, and the Ugly of Protein” (лекция, American Society of Bariatric Physicians (ASBP), October 31, 2006). Открыто по адресу http://drrosedale.com/resources/pdf/The_good_the_bad_and_the_ugly_of_protein.pdf.

8. Cuervo, A. M., et al. “Autophagy and Aging: The Importance of Maintaining ‘Clean’ Cells.” Autophagy 1, no. 3 (2005): 131–140.

9. Cheng, C. W., et al. “Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression.” Cell Stem Cell 14, no. 6 (2014): 810–823.

10. Brandhorst, S., et al. “A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.” Cell Metabolism 22, no. 1 (2015): 86–99.

11. Rosedale, R., E. C. Westman, and J. P. Konhilas. “Clinical Experience of a Diet Designed to Reduce Aging.” Journal of Applied Research 9, no. 4 (2009): 159–165.

Глава 5

1. Hancox, D. “The Unstoppable Rise of Veganism: How a Fringe Movement Went Mainstream.” The Guardian, April 1, 2018. Открыто по адресу www.theguardian.com/lifeandstyle/2018/apr/01/vegans-are-coming-millennials-health-climate-сhange-animal-welfare.

2. Zelman, K. M. “The Power of Plant Protein.” United Healthcare. Открыто по адресу www.uhc.com/health-and-wellness/nutrition/power-of-plant-protein.

3. “Lacalbumin.” https://en.wikipedia.org/wiki/Lactalbumin.

4. Bounous, G., and P. Gold. “The Biological Activity of Undenatured Dietary Whey Proteins: Role of Glutathione.” Clinical and Investigative Medicine 14, no. 4 (1991): 296–309.

5. Bounous, G., G. Batist, and P. Gold. “Whey Proteins in Cancer Prevention.” Cancer Letter 57, no. 2 (1991): 91–94.

6. Bounous, G., G. Batist, and P. Gold. “Immunoenhancing Property of Dietary Whey Protein in Mice: Role of Glutathione.” Clinical and Investigative Medicine 12, no. 3 (1989): 154–161.

7. Sekhar, R. V., et al. “Glutathione Synthesis Is Diminished in Patients with Uncontrolled Diabetes and Restored by Dietary Supplementation with Cysteine and Glycine.” Diabetes Care 34, no. 1 (2011): 162–167.

8. Berk, M., et al. “The Efficacy of N-Acetylcysteine as an Adjunctive Treatment in Bipolar Depression: An Open Label Trial.” Journal of Affective Disorders 135, no. 1–3 (2011): 389–394.

9. Dean, O., F. Giorlando, and M. Berk. “N-Acetylcysteine in Psychiatry: Current Therapeutic Evidence and Potential Mechanisms of Action.” Journal of Psychiatry & Neuroscience 36, no. 2 (2011): 78–86.

10. Breitkreutz, R., et al. “Massive Loss of Sulfur in HIV Infection.” AIDS Research and Human Retroviruses 16, no. 3 (2000): 203–209.

11. Bounous, G., et al. “Whey Proteins as a Food Supplement in HIV-Seropositive Individuals.” Clinical and Investigative Medicine 16, no. 3 (1993): 204–209.

12. Tse, H. N., et al. “High-Dose N-Acetylcysteine in Stable COPD: The 1-Year, Double-Blind, Randomized, Placebo-Controlled HIACE Study.” Chest 144, no. 1 (2013): 106–118; De Flora, S., C. Grassi, and L. Carati. “Attenuation of Influenza-Like Symptomatology and Improvement of Cell-Mediated Immunity with Long-Term N-Acetylcysteine Treatment.” European Respiratory Journal 10, no. 7 (1997): 1535–1541.

13. Droge, W. “Oxidative Stress and Ageing: Is Ageing a Cysteine Deficiency Syndrome?” Philosophical Transactions of the Royal Society B: Biological Sciences (London) 360, no. 1464 (2005): 2355–2372.

14. Op den Kamp, C. M., et al. “Muscle Atrophy in Cachexia: Can Dietary Protein Tip the Balance?” Current Opinion in Clinical Nutrition & Metabolic Care 12, no. 6 (2009): 611–616.

15. Marchesini, G., et al. “Nutritional Supplementation with Branched-Chain Amino Acids in Advanced Cirrhosis: A Double-Blind, Randomized Trial.” Gastroenterology 124, no. 7 (2003): 1792–1801.

16. D’Antona, G., et al. “Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice.” Cell Metabolism 12, no. 4 (2010): 362–372.

17. Hoppe, C., et al. “Differential Effects of Casein Versus Whey on Fasting Plasma Levels of Insulin, IGF-1 and IGF-1/IGFBP-3: Results from a Randomized 7-Day Supplementation Study in Prepubertal Boys.”